Cognitive
DSIP
DSIP is a synthetic nonapeptide corresponding to an endogenous peptide first associated with sleep regulation. It is used in neurobiology to investigate sleep–wake modulation, stress responses, and neuroendocrine signaling.
- Quantity
- Standard research vial
- Purity
- See COA
Standard $9.99 | Expedited $12.99 | Free standard over $200
Download Certificate of AnalysisResearch overview
Research Overview
Delta sleep-inducing peptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) has been studied for decades as a putative neuromodulator, with mixed and often conflicting findings regarding its role in sleep induction.[1–3] Modern use is primarily as a tool compound to explore peptide effects on EEG patterns, hypothalamic-pituitary axes, and mitochondrial function under defined conditions.
Molecular & Neurochemical Properties
DSIP’s small size and acidic character enable straightforward synthesis and labeling for receptor/binding studies.[1] It has been detected in several tissues, suggesting complex regulation and potential indirect actions.
Sleep, Stress & Mitochondrial Research
Experimental paradigms employ DSIP in animals and cell systems to monitor alterations in sleep architecture, stress hormone secretion, and oxidative phosphorylation.[2,4] Results inform hypotheses about peptide neuromodulation, without constituting validated clinical evidence.
