OSYRIS
AOD-9604

Metabolic

AOD-9604

$49.99

AOD-9604 is a synthetic peptide fragment of human growth hormone (hGH), comprising amino acids 176–191. Designed to focus on fat metabolism without affecting IGF-1 or glucose levels, it is widely studied in metabolic and obesity-related research. AOD-9604 is intended exclusively for controlled laboratory use in scientific research.

Quantity
10MG
Formula
C78H123N23O23S2
Mol. Weight
~1815.1 g/mol
Purity
See COA

Standard $9.99 | Expedited $12.99 | Free standard over $200

Download Certificate of Analysis
Research On This Compound

AOD-9604 — Isolating the Fat-Burning Fragment of Growth Hormone

9 min read · 5 citations · Metabolic
RESEARCH

AOD-9604 vs GLP-1 Agonists — Two Philosophies of Fat Metabolism

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Tirzepatide in Metabolic Research — Understanding Dual GIP/GLP-1 Agonism

Deep dive into tirzepatide-class dual receptor agonism research. GIP and GLP-1 pathways, clinical trial data, comparison with semaglutide. PubMed cited.
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Practical Guides
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Research overview

Product Overview:

Product Name: AOD-9604
Quantity: 10mg
Molecular Formula: C78H123N23O23S2
Molecular Weight: ~1815.1 g/mol
Research Use Only. Not for Human Consumption.

Research Applications:

  1. Metabolic and Lipolytic Regulation

AOD-9604 was developed by modifying the C-terminal segment (176–191) of human growth hormone (hGH). This region is believed to be responsible for hGH’s fat-reducing effects. Studies show AOD-9604 can stimulate lipolysis (fat breakdown) and inhibit lipogenesis (fat formation) in vitro without exerting significant effects on blood sugar or insulin sensitivity [1].

Its selective activation of lipolytic pathways without impacting IGF-1 makes it an important compound for researchers studying energy balance and fat metabolism mechanisms [2]. These features allow AOD-9604 to be studied in models where hGH-related mitogenic or diabetogenic effects are undesirable.

  1. Obesity and Adipose Tissue Models

In preclinical models, especially in obese rodents, AOD-9604 has demonstrated the ability to reduce body fat mass without altering lean muscle or organ weights [3]. It shows preferential activity on visceral adipose tissues and has been observed to enhance lipid mobilization even in high-calorie diet models. Importantly, this effect appears to occur independently of pituitary axis signaling, which distinguishes it from unmodified hGH.

This specificity makes AOD-9604 of interest in research focused on obesity, adipocyte biology, and endocrine-independent fat regulation pathways.

  1. Safety Profile in Preclinical Settings

According to animal studies and toxicological reviews, AOD-9604 did not exhibit mitogenic activity or increase in IGF-1 levels [4], key concerns often associated with full-length growth hormone analogs. These findings support its use in studies requiring metabolic modulation with reduced risk of off-target cellular proliferation.

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