Metabolic

SLU-PP-32

$74.99

SLU-PP-32 is offered as an experimental ligand within the emerging family of estrogen-related receptor (ERR) agonist tool compounds. It is strictly for exploratory research on nuclear receptor signaling, mitochondrial regulation, and oxidative metabolism.

Quantity: Standard research vial
Purity: See COA

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Research overview

Research Overview

Pan-ERR agonists such as SLU-PP-332 and SLU-PP-915 have been described as small molecules that directly bind ERRα/β/γ, activating transcriptional programs linked to oxidative metabolism and mitochondrial biogenesis.[1,2] SLU-PP-32 is positioned as a related investigative compound for extending structure–activity relationship (SAR) and pathway analyses in this domain.

ERR Activation & Mitochondrial Function

ERRs regulate genes involved in fatty acid oxidation, oxidative phosphorylation, and ATP production. Using characterized ligands, investigators assess changes in oxygen consumption rate, mitochondrial content, and expression of PGC-1α target genes in muscle, cardiac, and renal models.[1–3]

Exercise-Mimetic & Metabolic Models

Preclinical work evaluates how ERR activation influences endurance-associated gene signatures and metabolic syndrome phenotypes, strictly at the level of mechanistic discovery.[1–3] SLU-PP-32 is provided to support such ERR-focused research and should not be extrapolated to human use.